Characterizing fatigue in US, European and Latin-American adults with relapsing multiple sclerosis: a real-world study conducted using a novel disease specific scale

Relapsing multiple sclerosis (RMS) is an inflammatory demyelinating disorder of the central nervous system and the most common progressive neurologic disease of young adults worldwide. Fatigue is one of the most common symptoms of RMS and one of the main causes of patients’
quality-of-life (QoL) impairment. Considering its subjective aspect, using MS-specific patient reported outcomes to characterize it would grant a better understanding of its impact on patients’QoL.
This study aimed to measure fatigue in RMS patients from multiple countries using the Fatigue Symptoms and its impact Questionnaire-Relapsing Multiple Sclerosis (FSIQ-RMS).