An innovative patient-centric approach to integrate patients’ perspectives in the selection of Patient-Reported Outcomes

Patient-Reported Outcomes (PROs) are more and more used to support health products and
services development and their evaluation by health authorities. Their identification and selection
is thus a critical step in medical research to assess the medical conditions from the patients’
perspectives during clinical trials and clinical practices. Nevertheless, due to the wide variety of
instruments available, identifying the most suitable PROs to use in a specific context might be
complex.

There is no consensus on a standardized method to select PROs considering the medical and
scientific context and the regulatory recommendations. Patients’ perspectives being and more
considered in medical product development and in healthcare decision-making, it appears
valuable to take into account their preferences during the PRO selection and development process.
This research thus aimed at developing a patient-centric method for PROs selection and applied it
in a pilot study on lung cancer.