Presented at European Academy of Neurology (EAN) Congress Virtual Meeting (2021)
Collaborators: Janssen Global, NYU Langone Health
Authors: Wilczynski O, Katz E, Charvet L, Krupp L, Schuier M, Lair L
Fatigue is among the most frequent and disabling symptoms in patients with relapsing multiple sclerosis (RMS) and a main cause of impaired health-related quality of life. Fatigue is defined by subjective experience and measured via patient reported outcome (PRO) instruments. However, previously available PROs that assess MS-related fatigue do not meet instrument development and psychometric property requirements based on current guidelines. PRO tools that are MS-specific can improve understanding of MS fatigue and its impact, improving its clinical management. Fatigue Symptoms and Impacts Questionnaire – Relapsing Multiple Sclerosis (FSIQ-RMS), a novel MS-specific PRO instrument, was developed to assess both fatigue in patients with RMS and its impacts on physical activity, cognitive and emotional function and coping mechanisms.
Objective: The study was aimed at measuring MS fatigue symptoms and their impact on daily life in a real-world population using a self-administered online questionnaire including the RMS-specific FSIQ-RMS